James E. Brau (born 1946) is an American physicist at the University of Oregon (UO) who conducts research on elementary particles and fields. He founded the Oregon experimental high energy physics group in 1988 and served as director of the UO Center for High Energy Physics from 1997–2016. Prior to joining the Oregon faculty, he served in the Air Force and held positions at the Stanford Linear Accelerator Center and the University of Tennessee. He is a fellow of both the American Physical Society and also the American Association for the Advancement of Science. In 2006 he was appointed the Philip H. Knight Professor of Natural Science, an endowed professorship.