John Mark Verdier House, also known as Lafayette Building, is a building in Beaufort, South Carolina. It was built by John Mark Verdier, a French Huguenot, in 1804. The house typified Beaufort's gracious antebellum architectural style. It was a focal point of the town, a visible statement reflecting Verdier's significant wealth from trading indigo and growing sea island cotton. It was listed on the National Register of Historic Places in 1971. The house is owned and operated by the Historic Beaufort Foundation as a historic house museum.