Knudson hypothesis
The Knudson hypothesis, also known as the two-hit hypothesis or multiple-hit hypothesis, is the hypothesis that cancer is the result of accumulated mutations to a cell's DNA. It was first proposed by Carl O. Nordling in 1953, and later formulated by Alfred G. Knudson in 1971. Knudson's work led indirectly to the identification of cancer-related genes. Knudson won the 1998 Albert Lasker Clinical Medical Research Award for this work.
Wikipage disambiguates
Wikipage redirect
primaryTopic
Knudson hypothesis
The Knudson hypothesis, also known as the two-hit hypothesis or multiple-hit hypothesis, is the hypothesis that cancer is the result of accumulated mutations to a cell's DNA. It was first proposed by Carl O. Nordling in 1953, and later formulated by Alfred G. Knudson in 1971. Knudson's work led indirectly to the identification of cancer-related genes. Knudson won the 1998 Albert Lasker Clinical Medical Research Award for this work.
has abstract
A hipótese de Knudson é a hipó ...... sker de 1998 por seu trabalho.
@pt
Die Knudsonhypothese ist die A ...... zur Ausbildung der Erkrankung.
@de
Hipoteza Knudsona – hipoteza t ...... ał się być genem supresorowym.
@pl
La hipótesis de Knudson es la ...... vorecen la motilidad celular).
@es
L’hypothèse de Knudson est l'h ...... cogènes n'étaient pas touchés.
@fr
The Knudson hypothesis, also k ...... courage a malignant phenotype.
@en
Мутационная теория канцерогене ...... так и в соматических клетках.
@ru
クヌードソン仮説とは、癌は細胞のDNAに変異が蓄積した結果引 ...... 遺伝子による制御不能な増殖刺激がなければ、癌化は起こらない。
@ja
Wikipage page ID
Wikipage revision ID
740,922,281
subject
type
comment
A hipótese de Knudson é a hipó ...... sker de 1998 por seu trabalho.
@pt
Die Knudsonhypothese ist die A ...... for Clinical Medical Research.
@de
Hipoteza Knudsona – hipoteza t ...... ał się być genem supresorowym.
@pl
La hipótesis de Knudson es la ...... Albert Lasker por su trabajo.
@es
L’hypothèse de Knudson est l'h ...... ique en 1998 pour son travail.
@fr
The Knudson hypothesis, also k ...... Research Award for this work.
@en
Мутационная теория канцерогене ...... так и в соматических клетках.
@ru
クヌードソン仮説とは、癌は細胞のDNAに変異が蓄積した結果引 ...... 腫瘍を発症しやすいという疾病素因を有していることを発見した。
@ja
label
Hipoteza Knudsona
@pl
Hipótese de Knudson
@pt
Hipótesis de Knudson
@es
Hypothèse de Knudson
@fr
Knudson hypothesis
@en
Knudsonhypothese
@de
Мутационная теория канцерогенеза
@ru
クヌードソン仮説
@ja