Littleton High School is a public high school located at 56 King Street, Littleton, Massachusetts. It serves students in grades 9-12 from the town of Littleton.The building was opened in 2002. It was formerly located on the site of the current middle school from 1957–2002 on Russell Street. From 1924 to 1957 it was located on Shattuck Street in the building that now houses the town offices and the Reuben Hoar library. From 1957–1968 it was operated as a Junior/Senior high school and again from 1989–2002.