"Lost and Running" is a song by Australian rock group Powderfinger. It was released as the first single from the group's sixth studio album Dream Days at the Hotel Existence. It is the band's twenty-second single and peaked at No. 5 on the Australian chart, the group's second highest charting single after "My Happiness". It made its radio debut on 13 April on Triple J and was released to wide radio play and the band's MySpace on 16 April 2007. The single was officially released on 12 May 2007.