Mistake Creek is a locality in Isaac Region, Queensland, Australia. It has a primary school, which describes itself as "the only school for at least 70 kilometres", and there are other local organisations including Mistake Creek Progress Association and the Mistake Creek Playgroup. In 2013 the school had 11 students. The district takes its name from Mistake Creek, a tributary of the Belyando River, which was so named after Jerimiah Rolfe, an early local settler, believed his station to be on that river but later discovered it was on a tributary, which he named Mistake Creek.