Omega-atracotoxin
Omega-atracotoxin is an insect-specific neurotoxin produced by the Blue Mountains funnel-web spider. Its phylogenetic specificity derives from its ability to antagonise insect, but not vertebrate, voltage-gated calcium channels. Two spatially proximal amino acid residues, Asn(27) and Arg(35), form a contiguous molecular surface that is essential for toxin activity. It has been proposed that this surface of the beta-hairpin is a key site for interaction of the toxin with insect calcium channels.
primaryTopic
Omega-atracotoxin
Omega-atracotoxin is an insect-specific neurotoxin produced by the Blue Mountains funnel-web spider. Its phylogenetic specificity derives from its ability to antagonise insect, but not vertebrate, voltage-gated calcium channels. Two spatially proximal amino acid residues, Asn(27) and Arg(35), form a contiguous molecular surface that is essential for toxin activity. It has been proposed that this surface of the beta-hairpin is a key site for interaction of the toxin with insect calcium channels.
has abstract
Omega-atracotoxin is an insect ...... with insect calcium channels.
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Symbol
Omega-toxin
Wikipage page ID
31,911,373
Wikipage revision ID
723,705,004
InterPro
name
Omega-atracotoxin
PDB
subject
comment
Omega-atracotoxin is an insect ...... with insect calcium channels.
@en
label
Omega-atracotoxin
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