The Tontine Building is a historic mixed-use commercial and residential building at 500 Coolidge Highway (United States Route 5) in Guilford, Vermont. Built in 1819, it is a rare example of a Federal period commercial building in southeastern Vermont, and is one of only three buildings in the state known to have been financed by a tontine, a subscription-based investment model. The building was listed on the National Register of Historic Places in 2008. It has been rehabilitated and converted entirely into housing units.