Uxbridge Vine Street station opened on 8 September 1856 as Uxbridge Station and was the earliest of three railway stations in Uxbridge, London, in the UK. It was the northern terminus of the Great Western Railway Uxbridge branch from the main line at West Drayton. South from Uxbridge town centre the line ran near Whitehall Road and Cleveland Road. In November 1885, the Staines West branch opened sharing a short section of the Vine Street branch to connect to the main line. An intermediate station at Cowley opened in 1904.