The 1981 Mid-American Conference Baseball Tournament took place from May 16–18 of that year. The top four regular season finishers of the league's ten teams met in the double-elimination tournament held at Bill Theunissen Stadium in Mount Pleasant, Michigan. This was the first time the Mid-American Conference held a postseason tournament to determine a champion. Fourth seeded Eastern Michigan won the first tournament to earn the conference's automatic bid to the 1981 NCAA Division I Baseball Tournament.