2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine is a drug originally researched as a potential opioid analgesic, but was found to be inactive in this assay, and relatively toxic to mice. Subsequently it was found to possess activity as an agonist at nicotinic acetylcholine receptors during the course of work that ultimately led to the discovery of the anti-smoking drug varenicline.
primaryTopic
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine is a drug originally researched as a potential opioid analgesic, but was found to be inactive in this assay, and relatively toxic to mice. Subsequently it was found to possess activity as an agonist at nicotinic acetylcholine receptors during the course of work that ultimately led to the discovery of the anti-smoking drug varenicline.
has abstract
2,3,4,5-Tetrahydro-1,5-methano ...... ually the compound being sold.
@en
CAS number
230615-52-8
IUPAC name
2,3,4,5-tetrahydro-1,5-methano-1H-3-benzazepine
@en
Wikipage page ID
30,895,519
Wikipage revision ID
719,962,111
ChEMBL
ChemSpiderID
legal status
molecular weight
1.59227e+2
smiles
c13ccccc3C2CC1CNC2
StdInChIKey
COMHUAMOJSTCMM-UHFFFAOYSA-N
Verifiedfields
verifiedrevid
477,209,994
hypernym
comment
2,3,4,5-Tetrahydro-1,5-methano ...... anti-smoking drug varenicline.
@en
label
2,3,4,5-Tetrahydro-1,5-methano-1H-3-benzazepine
@en
