2β-Propanoyl-3β-(4-tolyl)-tropane
2β-Propanoyl-3β-(4-tolyl)-tropane also known as WF-11 or 2-PTT is a cocaine analogue 20 times more potent than cocaine at binding to the dopamine transporter with increased selectivity for the norepinephrine transporters. It also shows marked increase in metabolic stability. In contrast to the findings of cocaine effects, WF-11 has been shown to produce a uniform downregulation of tyrosine hydroxylase protein and activity gene expression with a regimen of use.
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2β-Propanoyl-3β-(4-tolyl)-tropane
2β-Propanoyl-3β-(4-tolyl)-tropane also known as WF-11 or 2-PTT is a cocaine analogue 20 times more potent than cocaine at binding to the dopamine transporter with increased selectivity for the norepinephrine transporters. It also shows marked increase in metabolic stability. In contrast to the findings of cocaine effects, WF-11 has been shown to produce a uniform downregulation of tyrosine hydroxylase protein and activity gene expression with a regimen of use.
has abstract
2β-Propanoyl-3β-(4-tolyl)-trop ...... ression with a regimen of use.
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CAS number
152783-29-4
IUPAC name
1-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]propan-1-one
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PubChem
thumbnail
Wikipage page ID
15,133,233
Wikipage revision ID
729,147,734
ChemSpiderID
molecular weight
2.71397e+2
smiles
CCC[C@@H]1[C@H]2CC[C@H]C[C@@H]1C3=CC=CC
StdInChIKey
PZEAJTAVRYLBTK-LHHMISFZSA-N
hypernym
comment
2β-Propanoyl-3β-(4-tolyl)-trop ...... ression with a regimen of use.
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label
2β-Propanoyl-3β-(4-tolyl)-tropane
@en