The 2006 Division 1 season was the 41st of the competition of the first-tier football in Senegal. The tournament was organized by the Fédération Sénégalaise de Football (Senegalese Football Federation). The season began on 5 January and finished on 15 July. AS Douanes won their third title. AS Douanes along with Port Autonome would compete in the 2007 CAF Champions League the following season. US Ouakam who won the 2006 Senegalese Cup participated in the 2007 CAF Confederation Cup, along with US Gorée. Compagnie sucrière sénégalaise, last place of Group A relegated to the second division with 14 points as they had a penalty that cost them three points by an undetermined reason, US Rail, last place of Group B was relegated with only 9 points.