The 2010 Autism Speaks 400 presented by Hershey's Milk & Milkshakes was the twelfth race of the 2010 NASCAR Sprint Cup Series season at Dover International Speedway in Dover, Delaware. It started at 1 p.m. EST on May 16, 2010. The 2010 Autism Speaks 400 was televised on Fox and was broadcast on MRN radio at 12 p.m. Martin Truex, Jr. started in the pole position. The race had eight different leaders, twenty lead changes, and five cautions. The winner of the race was Kyle Busch, while Jeff Burton and Matt Kenseth finished second and third respectively.