A-836,339
A-836,339 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist. It is selective for CB2, with Ki values of 0.64 nM at CB2 vs 270 nM at the psychoactive CB1 receptor, but while it exhibits selective analgesic, anti-inflammatory and anti-hyperalgesic effects at low doses, its high efficacy at both targets results in typical cannabis-like effects appearing at higher doses, despite its low binding affinity for CB1. In 2012 A-836,339 was detected via X-ray crystallography in a "dubious product" sold in Japan, though the product was described as a white powder, not herbal incense, it was suggested to be for human consumption.
primaryTopic
A-836,339
A-836,339 is a drug developed by Abbott Laboratories that acts as a potent cannabinoid receptor full agonist. It is selective for CB2, with Ki values of 0.64 nM at CB2 vs 270 nM at the psychoactive CB1 receptor, but while it exhibits selective analgesic, anti-inflammatory and anti-hyperalgesic effects at low doses, its high efficacy at both targets results in typical cannabis-like effects appearing at higher doses, despite its low binding affinity for CB1. In 2012 A-836,339 was detected via X-ray crystallography in a "dubious product" sold in Japan, though the product was described as a white powder, not herbal incense, it was suggested to be for human consumption.
has abstract
A-836,339 is a drug developed ...... d to be for human consumption.
@en
CAS number
959746-77-1
FDA UNII code
Z6Y1J258EG
IUPAC name
N-[3-(2-methoxyethyl)-4,5-dime ...... thylcyclopropane-1-carboxamide
@en
PubChem
thumbnail
Wikipage page ID
26,660,464
Wikipage revision ID
738,513,947
ChemSpiderID
26,286,892
legal CA
molecular weight
3.10454e+2
StdInChIKey
JKGIMVBQKSRTGX-UHFFFAOYSA-N
Verifiedfields
verifiedrevid
460,447,266
Watchedfields
hypernym
comment
A-836,339 is a drug developed ...... d to be for human consumption.
@en
label
A-836,339
@en