Adeno-associated virus
Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease. The virus causes a very mild immune response, lending further support to its apparent lack of pathogenicity. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell, although in the native virus some integration of virally carried genes into the host genome does occur. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Recent human clinical trials using AAV for gene therapy in the retina have shown promise.
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Adeno-associated virus
Adeno-associated virus (AAV) is a small virus which infects humans and some other primate species. AAV is not currently known to cause disease. The virus causes a very mild immune response, lending further support to its apparent lack of pathogenicity. Gene therapy vectors using AAV can infect both dividing and quiescent cells and persist in an extrachromosomal state without integrating into the genome of the host cell, although in the native virus some integration of virally carried genes into the host genome does occur. These features make AAV a very attractive candidate for creating viral vectors for gene therapy, and for the creation of isogenic human disease models. Recent human clinical trials using AAV for gene therapy in the retina have shown promise.
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Adeno-associated virus (AAV) i ...... defective, nonenveloped virus.
@en
Adeno-assoziierte Viren oder A ...... Variante nur 4,7kb verfügbar.
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I virus adeno-associati (AAV) ...... scio di particelle infettive..
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Los virus adeno-asociados (AAV ...... ospedadora que del adenovirus.
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Un virus adéno-associé (ou AAV ...... nératives en thérapie génique.
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Аденоассоциированный вирус (ан ...... ственных ферментов репликации.
@ru
アデノ随伴ウイルス(英: Adeno-associated ...... いた遺伝子治療やヒトの疾患モデル細胞の作成などに用いられる。
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violet
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734,424,562
image caption
Adeno-associated virus serotype 2 structure from 1LP3. One fivefold axis shown center.
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*Adeno-associated dependoparvovirus A
*Adeno-associated dependoparvovirus B
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Adeno-associated virus (AAV) i ...... the retina have shown promise.
@en
Adeno-assoziierte Viren oder A ...... umane Cytomegalievirus dienen.
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I virus adeno-associati (AAV) ...... rima volta con gli adenovirus.
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Los virus adeno-asociados (AAV ...... comprendiendo sólo dos genes:
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Un virus adéno-associé (ou AAV ...... er l'activité des cellules ner
@fr
Аденоассоциированный вирус (ан ...... х векторов для генной терапии.
@ru
アデノ随伴ウイルス(英: Adeno-associated ...... いた遺伝子治療やヒトの疾患モデル細胞の作成などに用いられる。
@ja
label
Adeno-associated virus
@en
Adeno-assoziierte Viren
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Virus adeno-asociado
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Virus adeno-associati
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Virus adéno-associé
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Аденоассоциированный вирус
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アデノ随伴ウイルス
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Adeno-associated virus
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