Aderbasib
Aderbasib (INN/USAN, codenamed INCB7839) is a sheddase inhibitor that may suppress tumor cell proliferation. Acting on multiple receptor classes and subclasses, aderbasib is observed to regulate the tumor necrosis factor of cancer cells.Aderbasib was being developed by Incyte as a potential adjunctive treatment for metastatic breast cancer. Development was halted in 2011 after positive findings from Phase II trials were contradicted by further research.
primaryTopic
Aderbasib
Aderbasib (INN/USAN, codenamed INCB7839) is a sheddase inhibitor that may suppress tumor cell proliferation. Acting on multiple receptor classes and subclasses, aderbasib is observed to regulate the tumor necrosis factor of cancer cells.Aderbasib was being developed by Incyte as a potential adjunctive treatment for metastatic breast cancer. Development was halted in 2011 after positive findings from Phase II trials were contradicted by further research.
has abstract
Aderbasib (INN/USAN, codenamed ...... tradicted by further research.
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ATC prefix
CAS number
791828-58-5
IUPAC name
methyl (6S,7S)-7-(hydroxycarba ...... spiro[2.5]octane-5-carboxylate
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PubChem
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Wikipage page ID
37,278,161
Wikipage revision ID
713,191,361
Alt
Skeletal formula of aderbasib
ChEMBL
ChemSpiderID
17,229,620
legal status
Investigational
molecular weight
routes of administration
smiles
COCN1CC2C[C@@H]CNO
StdInChIKey
DJXMSZSZEIKLQZ-IRXDYDNUSA-N
subject
hypernym
comment
Aderbasib (INN/USAN, codenamed ...... tradicted by further research.
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label
Aderbasib
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