Altropane
Altropane, (O-587, IACFT, 2β-carbomethoxy-3β-(4-fluorophenyl)-N-((E)-3-iodo-prop-2-enyl)tropane) is a phenyltropane derivative which acts as a potent dopamine reuptake inhibitor and long-acting stimulant drug. It has mainly been used as the 125I radiolabelled form for mapping the distribution of dopamine transporters in the brain, and consequently this has led to its development as a potential diagnostic tool for early detection of Parkinson's disease. It is also being investigated for potential use in the diagnosis and treatment of attention deficit hyperactivity disorder (ADHD).
primaryTopic
Altropane
Altropane, (O-587, IACFT, 2β-carbomethoxy-3β-(4-fluorophenyl)-N-((E)-3-iodo-prop-2-enyl)tropane) is a phenyltropane derivative which acts as a potent dopamine reuptake inhibitor and long-acting stimulant drug. It has mainly been used as the 125I radiolabelled form for mapping the distribution of dopamine transporters in the brain, and consequently this has led to its development as a potential diagnostic tool for early detection of Parkinson's disease. It is also being investigated for potential use in the diagnosis and treatment of attention deficit hyperactivity disorder (ADHD).
has abstract
Altropane, (O-587, IACFT, 2β-c ...... hyperactivity disorder (ADHD).
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ATC prefix
CAS number
180468-34-2
IUPAC name
Methyl (1R,2S,3S,5S)-3-(4-fluo ...... clo[3.2.1]octane-2-carboxylate
@en
PubChem
thumbnail
Wikipage page ID
18,646,192
Wikipage revision ID
713,191,906
ChemSpiderID
molecular weight
4.292694e+2
smiles
COC[C@@H]1[C@H]2CC[C@H]C[C@@H]1C3=CC=CF
StdInChIKey
GTQLIPQFXVKRKJ-UNSMHXHVSA-N
verifiedrevid
449,574,326
Watchedfields
comment
Altropane, (O-587, IACFT, 2β-c ...... hyperactivity disorder (ADHD).
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label
Altropane
@en