The American College of Surgeons Oncology Group (ACOSOG) is a clinical trial cooperative group supported publicly by the National Cancer Institute (NCI). Established during the 1990s, ACOSOG has a different mission when compared to other cooperative groups. For the most part, ACOSOG focuses on the effects of surgery on patients with malignant tumors. Other cooperative groups like COG, ECOG, and SWOG, tend to emphasize the role of radiotherapy in patients with metastatic cancers. Nearly all age groups are considered in ACOSOG studies; however, middle-aged to senior adults tend to comprise the basis for most of the research conducted with ACOSOG protocols. Children who necessitate surgery for resection of malignant tumors typically fall under the auspices of COG. Currently, ACOSOG offices ar