Appoquinimink Friends Meetinghouse, also known as the Odessa Friends Meetinghouse, is a very small but historic Quaker meetinghouse on Main Street in Odessa, Delaware. It was built in 1785 by David Wilson and added to the National Register of Historic Places in 1972. Members of the meeting, including John Hunn and his cousin John Alston, were active in the Underground Railroad and Harriet Tubman may have hid in the meetinghouse. Measuring about 20 feet (6.1 m) by 22 feet (6.7 m), it may be the smallest brick house of worship in the United States.