Aztlanolagus is an extinct monotypic genus of rabbit that lived during the Quaternary of the Southern to Southwestern United States and northern Mexico. Aztlanolagus agilis is currently the only recognized species, though differences among recovered fossils suggest that there may have been other species. The generic name refers to Aztlán, the legendary place of origin of the Nahua peoples as recorded in the mythological accounts of the Aztecs and other Nahua groups. By some traditions, this legendary locale is placed in the border regions of the Southwestern United States and adjacent northern Mexico.