BMS-564,929
BMS-564,929 is an investigational selective androgen receptor modulator, which is being developed by Bristol-Myers Squibb for treatment of the symptoms of age-related decline in androgen levels in men ("andropause"). These symptoms may include depression, loss of muscle mass and strength, reduction in libido and osteoporosis. Treatment with exogenous testosterone is effective in counteracting these symptoms but is associated with a range of side effects, the most serious of which is enlargement of the prostate gland, which can lead to benign prostatic hypertrophy and even prostate cancer. This means there is a clinical need for selective androgen receptor modulators, which produce anabolic effects in some tissues such as muscle and bone, but without stimulating androgen receptors in the pr
primaryTopic
BMS-564,929
BMS-564,929 is an investigational selective androgen receptor modulator, which is being developed by Bristol-Myers Squibb for treatment of the symptoms of age-related decline in androgen levels in men ("andropause"). These symptoms may include depression, loss of muscle mass and strength, reduction in libido and osteoporosis. Treatment with exogenous testosterone is effective in counteracting these symptoms but is associated with a range of side effects, the most serious of which is enlargement of the prostate gland, which can lead to benign prostatic hypertrophy and even prostate cancer. This means there is a clinical need for selective androgen receptor modulators, which produce anabolic effects in some tissues such as muscle and bone, but without stimulating androgen receptors in the pr
has abstract
BMS-564,929 is an investigatio ...... are currently being developed.
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CAS number
627530-84-1
DrugBank
FDA UNII code
9BLW27W4X7
IUPAC name
4-[(7R,7aS)-7-hydroxy-1,3-diox ...... -2-chloro-3-methylbenzonitrile
@en
PubChem
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Link from a Wikipage to an external page
Wikipage page ID
19,943,267
Wikipage revision ID
729,585,850
ChEMBL
ChemSpiderID
legal status
Investigational new drug
molecular weight
3.05716e+2
smiles
CC1=CN2C[C@@H]3[C@@H]O
StdInChIKey
KEJORAMIZFOODM-PWSUYJOCSA-N
Verifiedfields
verifiedrevid
424,678,818
subject
hypernym
comment
BMS-564,929 is an investigatio ...... g androgen receptors in the pr
@en
label
BMS-564,929
@en