Barker House is a historic home located at Edenton, Chowan County, North Carolina. The original house was built about 1782, and expanded during the 19th century. It is a 2 1/2-story frame dwelling with Georgian, Federal, and Greek Revival style design elements. It sits on a brick foundation and has at both ends a pair of single-shoulder exterior chimneys. The front facade features a full-length, two-tier porch carried on superimposed fluted pillars under a shed roof. It was listed on the National Register of Historic Places in 1972.