Busbie Castle was situated in what is now known as Knockentiber (Scottish Gaelic: Cnoc an Tobair, hill of the well), a village in East Ayrshire, Parish of Kilmaurs, Scotland. Knockentiber is 2 miles (3.2 km) WNW of Kilmarnock and 1/2 mile NE of Crosshouse. The castle overlooked the Carmel Glen and its Burn, which runs into the River Irvine, a mile or so to the south, after passing through the old Busbie Mill.