CTEP
CTEP is a research drug developed by Hoffmann-La Roche that acts as a selective allosteric antagonist of the metabotropic glutamate receptor subtype mGluR5, binding with nanomolar affinity and over 1000 times selectivity over all other receptor targets tested. In animal studies it was found to have a high oral bioavailability and a long duration of action, lasting 18 hours after a single dose, giving it considerably improved properties over older mGluR5 antagonists such as MPEP and fenobam.
primaryTopic
CTEP
CTEP is a research drug developed by Hoffmann-La Roche that acts as a selective allosteric antagonist of the metabotropic glutamate receptor subtype mGluR5, binding with nanomolar affinity and over 1000 times selectivity over all other receptor targets tested. In animal studies it was found to have a high oral bioavailability and a long duration of action, lasting 18 hours after a single dose, giving it considerably improved properties over older mGluR5 antagonists such as MPEP and fenobam.
has abstract
CTEP is a research drug develo ...... ists such as MPEP and fenobam.
@en
IUPAC name
2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine
@en
PubChem
thumbnail
Wikipage page ID
34,541,581
Wikipage revision ID
701,948,386
ChemSpiderID
IUPHAR ligand
molecular weight
3.91774e+2
smiles
Clc2ccC#Cc1ncn-cccc3OCF
StdInChIKey
GOHCTCOGYKAJLZ-UHFFFAOYSA-N
hypernym
comment
CTEP is a research drug develo ...... ists such as MPEP and fenobam.
@en
label
CTEP
@en
