Charles H. Ireland House was a historic home located at Greensboro, Guilford County, North Carolina. It was built in 1904, and was a large 2 1/2-story, three bay, granite, brick, and frame structure with Colonial Revival, Classical Revival and Queen Anne style design elements. It featured a pedimented two-story portico with Ionic order columns and a steeply pitched gambrel roof. It was destroyed by fire February 2, 1996. It was listed on the National Register of Historic Places in 1979.