Chloroprednisone
Chloroprednisone is a topical glucocorticoid first reported in 1960. It is a chlorinated derivative of prednisone. The acetate ester prodrug, chloroprednisone 21-acetate, was sold under the brand name Topilan as an anti-inflammatory agent. There is little published about chloroprednisone. This may be due to limited activity topically because the skin lacks the necessary activating enzyme 11-Beta hydroxysteroid dehydrogenase. Systemically, this agent's activity on Glucocorticoid receptors may not have competed with agents like Fludrocortisone or Dexamethasone.
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Chloroprednisone
Chloroprednisone is a topical glucocorticoid first reported in 1960. It is a chlorinated derivative of prednisone. The acetate ester prodrug, chloroprednisone 21-acetate, was sold under the brand name Topilan as an anti-inflammatory agent. There is little published about chloroprednisone. This may be due to limited activity topically because the skin lacks the necessary activating enzyme 11-Beta hydroxysteroid dehydrogenase. Systemically, this agent's activity on Glucocorticoid receptors may not have competed with agents like Fludrocortisone or Dexamethasone.
has abstract
Chloroprednisone is a topical ...... drocortisone or Dexamethasone.
@en
ATC prefix
ATC suffix
ATC supplemental
(combination with antiinfectives)
CAS number
52080-57-6
IUPAC name
(6α)-6-Chloro-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
@en
PubChem
thumbnail
Wikipage page ID
36,048,907
Wikipage revision ID
713,198,491
ChemSpiderID
molecular weight
3.92873e+2
smiles
O=C[C@@]3CC[C@H]2[C@@H]4C[C@H]\C1=C\C\C=C/[C@]1[C@H]4CC[C@@]23C
StdInChIKey
NPSLCOWKFFNQKK-ZPSUVKRCSA-N
hypernym
comment
Chloroprednisone is a topical ...... drocortisone or Dexamethasone.
@en
label
Chloroprednisone
@en