Core binding factor

The Core binding factor (CBF) is a group of heterodimeric transcription factors. Core binding factors are composed of: * a non-DNA-binding CBFβ chain (CBFB) * a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)

Core binding factor

The Core binding factor (CBF) is a group of heterodimeric transcription factors. Core binding factors are composed of: * a non-DNA-binding CBFβ chain (CBFB) * a DNA-binding CBFα chain (RUNX1, RUNX2, RUNX3)