Cucurbita pedatifolia is a xerophyte plant species of the genus Cucurbita. It is native to Querétaro, Mexico. It has not been domesticated. While C. pedatifolia has been cross bred, results have met with limited success. It does not cross well with other species of Cucurbita. It is a close relative of Cucurbita radicans. Geographic location and genetics make it highly likely that Cucurbita scabridifolia is a naturally occurring hybrid of Cucurbita foetidissima and C. pedatifolia. It also has some mesophyte traits may represent a transitional state between the mesophytic Cucurbita and the mesophytic Cucurbita.