Cyproterone

Cyproterone (INN) (developmental code name SH-80881), also known as 1,2α-methylene-6-chloro-δ6-17α-hydroxyprogesterone is a steroidal, pure antiandrogen that was studied in the mid to late 1960s and early 1970s but was never marketed for medical use. It is the free alcohol or non-17α-acetylated analogue of cyproterone acetate (CPA), an antiandrogen, progestin, and antigonadotropin that was introduced instead and is widely used clinically. Along with benorterone, BOMT, and flutamide, cyproterone was one of the first pure antiandrogens to be developed.

Cyproterone

Cyproterone (INN) (developmental code name SH-80881), also known as 1,2α-methylene-6-chloro-δ6-17α-hydroxyprogesterone is a steroidal, pure antiandrogen that was studied in the mid to late 1960s and early 1970s but was never marketed for medical use. It is the free alcohol or non-17α-acetylated analogue of cyproterone acetate (CPA), an antiandrogen, progestin, and antigonadotropin that was introduced instead and is widely used clinically. Along with benorterone, BOMT, and flutamide, cyproterone was one of the first pure antiandrogens to be developed.