Etazolate
Etazolate (SQ-20,009, EHT-0202) is an anxiolytic drug which is a pyrazolopyridine derivative and has unique pharmacological properties. It acts as a positive allosteric modulator of the GABAA receptor at the barbiturate binding site, as an adenosine antagonist of the A1 and A2 subtypes, and as a phosphodiesterase inhibitor selective for the PDE4 isoform. It is currently in clinical trials for the treatment of Alzheimer's disease.
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Etazolate
Etazolate (SQ-20,009, EHT-0202) is an anxiolytic drug which is a pyrazolopyridine derivative and has unique pharmacological properties. It acts as a positive allosteric modulator of the GABAA receptor at the barbiturate binding site, as an adenosine antagonist of the A1 and A2 subtypes, and as a phosphodiesterase inhibitor selective for the PDE4 isoform. It is currently in clinical trials for the treatment of Alzheimer's disease.
has abstract
Etazolate (SQ-20,009, EHT-0202 ...... atment of Alzheimer's disease.
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ATC prefix
CAS number
51022-77-6
FDA UNII code
I89Y79062L
IUPAC name
Ethyl 1-ethyl-4-[2-(propan-2-ylidene)hydrazinyl]-1H-pyrazolo[3,4-b]pyridine-5-carboxylate
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PubChem
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Wikipage page ID
16,399,269
Wikipage revision ID
721,928,881
ChEMBL
ChemSpiderID
IUPHAR ligand
legal status
molecular weight
smiles
CCN1C2=NC=CCOCC
subject
comment
Etazolate (SQ-20,009, EHT-0202 ...... atment of Alzheimer's disease.
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label
Etazolate
@en