Euphorbia antisyphilitica is a species of spurge that is native to the Trans-Pecos of Texas and southern New Mexico in the United States as well as Chihuahua, Coahuila, Hidalgo, and Querétaro in Mexico. Common names include candelilla and wax plant, but the latter is more often applied to members of the unrelated genus Hoya. It is shrubby and has densely clustered, erect, essentially leafless stems that are covered in wax to prevent transpiration.