Fenobam
Fenobam is an imidazole derivative developed by McNeil Laboratories in the late 1970s as a novel anxiolytic drug with an at-the-time-unidentified molecular target in the brain. Subsequently, it was determined that fenobam acts as a potent and selective negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5, and it has been used as a lead compound for the development of a range of newer mGluR5 antagonists.
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Fenobam
Fenobam is an imidazole derivative developed by McNeil Laboratories in the late 1970s as a novel anxiolytic drug with an at-the-time-unidentified molecular target in the brain. Subsequently, it was determined that fenobam acts as a potent and selective negative allosteric modulator of the metabotropic glutamate receptor subtype mGluR5, and it has been used as a lead compound for the development of a range of newer mGluR5 antagonists.
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Fenobam is an imidazole deriva ...... eil Laboratories in the 1970s.
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IUPAC name
1-(3-Chlorophenyl)-3-(3-methyl-5-oxo-4H-imidazol-2-yl)urea
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737,244,865
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Fenobam is an imidazole deriva ...... e of newer mGluR5 antagonists.
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label
Fenobam
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