The George B. Cox House is a historic residence in Cincinnati, Ohio, United States. An Italianate building constructed in 1894, this two-and-a-half story building was built as the home of leading Hamilton County politician George B. Cox. In 2010, arrangements were made to transfer ownership of the property to the Public Library of Cincinnati and Hamilton County, which announced plans to convert it into a branch library to serve the surrounding Clifton neighborhood. The library stated that the Cox House would replace a small storefront that previously served the Clifton branch.