Grosse Isle (French: Grosse Île, "big island"), is located in Gulf of St. Lawrence in Quebec, Canada. It is one of the islands of the 21-island Isle-aux-Grues archipelago. It is part of the municipality of Saint-Antoine-de-l'Isle-aux-Grues, located in the Chaudière-Appalaches region of the province. It is estimated that in total, from when it was set up in 1832 to the closing in 1932, almost 500,000 Irish immigrants passed through Grosse Isle on their way to Canada.