Halofantrine
Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin in vitro, suggesting a possible mechanism of action. Halofantrine has also been shown to bind to plasmpesin, a haemoglobin degrading enzyme unique to the malarial parasites.
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Halofantrine
Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin in vitro, suggesting a possible mechanism of action. Halofantrine has also been shown to bind to plasmpesin, a haemoglobin degrading enzyme unique to the malarial parasites.
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Halofantrine is a drug used to ...... cinal chemist William Colwell.
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Halofantryna (łac. Halofantrin ...... lecany w profilaktyce choroby.
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La alofantrina è un composto ...... cida ematico ad azione rapida.
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ATC prefix
ATC suffix
CAS number
69756-53-2
DrugBank
FDA UNII code
Q2OS4303HZ
IUPAC name
3-(Dibutylamino)-1-[1,3-dichloro-6-(trifluoromethyl)-9-phenanthryl]-1-propanol
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PubChem
thumbnail
Wikipage page ID
Wikipage revision ID
729,793,562
ChEMBL
ChemSpiderID
elimination half-life
-864000.0
MedlinePlus
metabolism
molecular weight
5.00423e+2
protein bound
routes of administration
smiles
FCc3ccc2cCCCNCCCC
StdInChIKey
FOHHNHSLJDZUGQ-UHFFFAOYSA-N
tradename
verifiedrevid
461,766,301
hypernym
comment
Halofantrine is a drug used to ...... que to the malarial parasites.
@en
Halofantryna (łac. Halofantrin ...... lecany w profilaktyce choroby.
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La alofantrina è un composto ...... cida ematico ad azione rapida.
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label
Alofantrina
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Halofantrine
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Halofantryna
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