Hernán Pérez de Quesada, sometimes spelled as De Quezada, (Granada, Castile, ~1500 - Caribbean Sea, off the coast of Cabo de la Vela, New Kingdom of Granada, 1544) was a Spanish conquistador. Second in command of the army of his elder brother, Gonzalo Jiménez de Quesada, Hernán was part of the first European expedition towards the inner highlands of the Colombian Andes. The harsh journey, taking almost a year and many deaths, led through the departments Magdalena, Cesar, Santander, Boyacá, Cundinamarca and Huila of present-day Colombia between 1536 and 1539 and, without him, Meta, Caquetá and Putumayo of Colombia and northern Peru and Ecuador between 1540 and 1542.