Idoxuridine
Idoxuridine is an anti-herpesvirus antiviral drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity. It was synthesized by William Prusoff in the late 1950s. Initially developed as an anticancer drug, idoxuridine became the first antiviral agent in 1962.
5-iodo-2'-deoxyuridineATC code D06BB01ATC code J05AB02ATC code S01AD01ATCvet code QD06BB01ATCvet code QJ05AB02ATCvet code QS01AD01AntizonaDendridEmanilHeratilHerpe-GelHerpes-GelHerpesilHerpidHerpiduHerplexHerplex LiquifilmIdexurIdoxeneIdu OculosIducherIduleaIduridinIduviranIododeoxyuridineJoddeoxiuridinKerecidOphthalmadineSpectanefranStoxilSynmiolVirudox
Wikipage redirect
primaryTopic
Idoxuridine
Idoxuridine is an anti-herpesvirus antiviral drug. It is a nucleoside analogue, a modified form of deoxyuridine, similar enough to be incorporated into viral DNA replication, but the iodine atom added to the uracil component blocks base pairing. It is used only topically due to cardiotoxicity. It was synthesized by William Prusoff in the late 1950s. Initially developed as an anticancer drug, idoxuridine became the first antiviral agent in 1962.
has abstract
Idoxuridin (2′-Desoxy-5-iod-ur ...... ei der DNA-Synthese der Viren.
@de
Idoxuridina o idossuridina è u ...... lmica al 2% di concentrazione.
@it
Idoxuridine is an anti-herpesv ...... first antiviral agent in 1962.
@en
La idoxuridina es un análogo t ...... timetabolito de la pirimidina.
@es
إيدوكسوريدين هي العقاقير المضا ...... ل مضاد للفيروسات في عام 1962..
@ar
イドクスウリジン（英語：Idoxuridine、略：IDU） ...... て開発さ���たが、1962年に最初の抗ウイルス剤となった。
@ja
ATC prefix
ATC suffix
ATC supplemental
CAS number
DrugBank
FDA UNII code
LGP81V5245
IUPAC name
1-[(2R,4S,5R)-4-hydroxy-5-(hyd ...... tetrahydropyrimidine-2,4-dione
@en
PubChem
Wikipage page ID
Wikipage revision ID
734,290,252
ChemSpiderID
10,481,938
MedlinePlus
molecular weight
3.54099e+2
NIAID ChemDB
pregnancy category
routes of administration
smiles
I\C1=C\NC2C[C@H][C@@H]O2
StdInChIKey
XQFRJNBWHJMXHO-GFCOJPQKSA-N
synonyms
Iododeoxyuridine; IUdR
Verifiedfields
verifiedrevid
461,936,439
hypernym
comment
Idoxuridin (2′-Desoxy-5-iod-ur ...... ei der DNA-Synthese der Viren.
@de
Idoxuridina o idossuridina è u ...... i crema (non destinata a uso o
@it
Idoxuridine is an anti-herpesv ...... first antiviral agent in 1962.
@en
La idoxuridina es un análogo t ...... timetabolito de la pirimidina.
@es
إيدوكسوريدين هي العقاقير المضا ...... ل مضاد للفيروسات في عام 1962..
@ar
イドクスウリジン（英語：Idoxuridine、略：IDU） ...... として開発されたが、1962年に最初の抗ウイルス剤となった。
@ja
label
Idoxuridin
@de
Idoxuridina
@es
Idoxuridina
@it
Idoxuridine
@en
إيدوكسوريدين
@ar
イドクスウリジン
@ja
