JUNQ and IPOD
JUNQ and IPOD are types of cytosolic protein inclusion bodies in eukaryotes. Neurodegenerative diseases, such as Parkinson's, Alzheimer's, and Huntington's, are associated and correlated with protein aggregation and accumulation of misfolded proteins in inclusion bodies. For many years, protein aggregation was considered a random process by which misfolded proteins stick to each other to form inclusions (imagine a bundle of hairs haphazardly piling up in a corner of a room). Moreover, protein aggregates were thought to be toxic agents and the cause for neuronal dysfunction and death. However, recent studies, using advanced methods (i.e. Fluorescence microscopy), show that protein aggregation may actually be a tightly regulated, organized process, by which the cell protects itself from toxi
JUNQ and IPOD
JUNQ and IPOD are types of cytosolic protein inclusion bodies in eukaryotes. Neurodegenerative diseases, such as Parkinson's, Alzheimer's, and Huntington's, are associated and correlated with protein aggregation and accumulation of misfolded proteins in inclusion bodies. For many years, protein aggregation was considered a random process by which misfolded proteins stick to each other to form inclusions (imagine a bundle of hairs haphazardly piling up in a corner of a room). Moreover, protein aggregates were thought to be toxic agents and the cause for neuronal dysfunction and death. However, recent studies, using advanced methods (i.e. Fluorescence microscopy), show that protein aggregation may actually be a tightly regulated, organized process, by which the cell protects itself from toxi
has abstract
JUNQ and IPOD are types of cyt ...... ion to an aggregate inclusion.
@en
JUNQとIPODは、真核生物の細胞質に見られるタンパク質の ...... スフォールドタンパク質から細胞内環境を保護しているのである。
@ja
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Wikipage page ID
36,066,758
Wikipage revision ID
723,112,757
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hypernym
comment
JUNQ and IPOD are types of cyt ...... cell protects itself from toxi
@en
JUNQとIPODは、真核生物の細胞質に見られるタンパク質の ...... rotein Deposit、意味:不溶性タンパク質保管所)
@ja
label
JUNQ and IPOD
@en
JUNQとIPOD
@ja