Jay Hollister Upton (April 28, 1879 – December 30, 1938) was an American politician and attorney from the state of Oregon. He was a conservative Republican who served two years in the Oregon House of Representatives; and later, fourteen years in the Oregon State Senate. In the senate, Upton represented a large rural district in eastern Oregon. He served as President of the Oregon Senate during the 1923 legislative session. Upton ran for Governor of Oregon and for the United States Congress from Oregon's 2nd congressional district, but lost both of those elections.