Levocabastine
Levocabastine (trade name Livostin) is a selective second-generation H1 receptor antagonists which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis. As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS2, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor.
primaryTopic
Levocabastine
Levocabastine (trade name Livostin) is a selective second-generation H1 receptor antagonists which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis. As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS2, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor.
has abstract
La lévocabastine (R50547) est ...... e avec la spécialité Levophta.
@fr
Levocabastin ist ein Arzneisto ...... scher Erkrankungen eingesetzt.
@de
Levocabastine (trade name Livo ...... ar allergic ocular conditions.
@en
ATC prefix
ATC suffix
CAS number
79516-68-0
DrugBank
FDA UNII code
H68BP06S81
IUPAC name
(3S,4R)-1-[cis-4-cyano-4-(4-fl ...... yl-4-piperidinecarboxylic acid
@en
PubChem
thumbnail
Wikipage page ID
Wikipage revision ID
738,001,942
ChEMBL
ChemSpiderID
16,736,421
IUPHAR ligand
legal status
molecular weight
4.20519e+2
pregnancy AU
routes of administration
Ophthalmic, intranasal
smiles
Fc1ccc[C@]2C#N
StdInChIKey
ZCGOMHNNNFPNMX-KYTRFIICSA-N
tradename
Verifiedfields
verifiedrevid
462,090,822
Watchedfields
subject
hypernym
comment
La lévocabastine (R50547) est ...... e avec la spécialité Levophta.
@fr
Levocabastin ist ein Arzneisto ...... scher Erkrankungen eingesetzt.
@de
Levocabastine (trade name Livo ...... or the study of this receptor.
@en
label
Levocabastin
@de
Levocabastine
@en
Lévocabastine
@fr