Melon necrotic spot virus (MNSV) is a virus that belongs to the Carmovirus genus of viruses in the Tombusviridae family. It has been observed in several countries of the Americas, Africa, Asia, and Europe. It is considered to be an endemic virus in greenhouses and field productions of Cucurbitaceae crops, including melon (Cucumis melo), cucumber (Cucumbis sativus), and watermelon (Citrullus lanatus). MNSV is mainly spread through infected soil, seedlings, insects, and by the root-inhabiting fungus vector Olpidium bornovanus. Symptoms vary between Curbitaceae crops, but generally consist of chlorosis, brown necrotic lesions, leaf wilt, fruit decay, and plant death. Management of the disease consists of preventing infection by rotating fields and crops, steam sterilization, and disposal of i