Misty Plowright is one of the first two openly transgender people in the United States to be a candidate representing a major political party for a national office. She was the first openly transgender candidate to win a major party primary for the United States House of Representatives. She won the Democratic primary vote in Colorado and will go on to challenge Republican Doug Lamborn's five-term Congressional seat representing Colorado's Fifth District in the November 8, 2016, United States House of Representatives elections.