The Mrs. Lydia Johnson House is a historic residence located in Maquoketa, Iowa, United States. This house is a fine example of the Queen Anne style built during the economic boom years in the city's development. Built in 1895, the 2½-story house features a complex irregular composition, a corner tower, wrap-around porch, a small porch on the second floor above the main porch, various window shapes and sizes, and textured wall surfaces on the exterior. Little is now about the Johnson family who built it, but its notability is derived from the architecture. The house was listed on the National Register of Historic Places in 1991.