Poecilanthrax is a large, primarily Nearctic genus of flies belonging to the family Bombyliidae (bee-flies). These are large to large robust flies with a body length of 8–14 mm. They have large elongate pictured wings, with 2 or 3 submarginal cells and no vein M2. The abdomen is moderately lengthened, with 7 visible tergites. The front tarsi are reduced, and the tibia smooth. The larvae feed on the moth larva of members of the family Noctuidae. Adults feed on pollen.