Protoparvovirus is a genus of viruses in the subfamily Parvovirinae of the virus family Parvoviridae. Vertebrates serve as natural hosts. There are currently five species in this genus including the type species Rodent protoparvovirus 1. This genus includes canine parvovirus, which causes gastrointestinal tract damage in puppies that is about 80% fatal. Until 2014, the genus was called Parvovirus, but it was renamed to eliminate confusion between members of this genus and members of the entire family Parvoviridae.