St. Paul's Episcopal Church is located at North Hamilton and Mansion streets on the west side of Mansion Square in Poughkeepsie, New York, United States. It is a stone church in the Norman-Gothic Revival styles built in the late 19th century. Designed by New York City architect Emlen Littell, it has had additions and renovations by other well-known architects, such as Frederick Clarke Withers and Richard Upjohn. The interior treatment was done by Tiffany & Co. in the early 20th century. In 1982 it was added to the National Register of Historic Places.