Thomas Wise (died March 1641) of Sydenham in Devon, was an English politician who sat in the House of Commons of England at various times between 1625 and 1641. Wise was the son of Sir Thomas Wise (d.1629) by his wife Margaret Stafford, daughter of Robert Stafford of Stowford, Devon. His father had been an MP and had built houses at Mount Wise at Stoke Damerel and at Sydenham. In 1625 Wise was nominated by Robert Rolle (d.1633) of Heanton Satchville, Petrockstowe, Devon, as a Member of Parliament for his pocket borough of Callington, which manor had been acquired by him in 1601. Thus in 1625 he served in the Useless Parliament. He was then elected MP for Bere Alston in the parliaments of King Charles of 1625, 1626 and 1628 to 1629. Wise inherited the family estates on the death of his fath