Activating p38 MAPK: new tricks for an old kinase.Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterConcepts and challenges in cancer risk prediction for the space radiation environmentDeath and decoy receptors and p53-mediated apoptosis.DNA-damage inducible genes.Functional genomics as a window on radiation stress signalingGene expression profiles for monitoring radiation exposure.Genomic instability, centrosome amplification, cell cycle checkpoints and Gadd45aGenotoxic-stress-response genes and growth-arrest genes. gadd, MyD, and other genes induced by treatments eliciting growth arrestMammalian genes induced by radiation; activation of genes associated with growth control.p38 and Chk1 kinases: different conductors for the G(2)/M checkpoint symphonyp53-mediated protective responses to UV irradiation.Radiation metabolomics and its potential in biodosimetryRegulation of translation initiation following stress.Roles for p53 in growth arrest and apoptosis: putting on the brakes after genotoxic stressSignaling events controlling the molecular response to genotoxic stress.Surrogate tissue analysis: monitoring toxicant exposure and health status of inaccessible tissues through the analysis of accessible tissues and cellsThe complexity of radiation stress responses: analysis by informatics and functional genomics approaches.The dark side of light: the damaging effects of UV rays and the protective efforts of MAP kinase signaling in the epidermisToxicogenomics: overview and potential applications for the study of non-covalent DNA interacting chemicalsVoluntary exploratory data submissions to the US FDA and the EMA: experience and impact.
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Albert Fornace
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A-7407-2008
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Albert J Fornace
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Albert J Fornace
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Albert J Fornace
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Albert J Fornace
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Albert J Fornace
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