Astbury Centre for Structural Molecular Biology
research centre at the University of Leeds
Adam NelsonAlan BerryAlex BreezeAlex John O'NeillAlison E. AshcroftAlison BakerAmit KumarAndreas KiesslingAndrew J WilsonArwen PearsonBrendan FarrellColin W G FishwickDaniel L. HurdissDarren C. TomlinsonDavid J. BrockwellDavid R. WestheadDejian ZhouElton ZeqirajEmanuele PaciFrank SobottGlyn HemsworthJohn BarrKarl A. HassanKavitha ThirumuruganKenneth J McDowallLars JeukenMark HarrisMichael E. WebbMichael J. McPhersonNeil RansonNicola StonehousePaul A BealesPeter G. AdamsPeter HendersonPeter J KnightPeter StockleyRebecca F ThompsonRichard BaylissRichard FosterRobin S. Bon
affiliation
Compatibility rules for glycosaminoglycan-amyloid interactionsDynamic mechanisms of FGFR activation in cancer by kinase mutationsEnabling ultra-high resolution hydrogen/deuterium exchange for challenging biomedical systemsExploiting the distinctive catalysis of chemically modified enzymesExploiting the structure of integral membrane pyrophosphatasesGlobal control of rhythmic gene expression by the transcription factor LHYHow do ATP-independent chaperones assist OMP folding and assembly? Insights from mass spectrometry and other approachesIn vivo selection of bioprocessable biopharmaceuticalsInterrogating the folding and function of membrane proteins by mass spectrometryInvestigating E. coli cell envelope proteins and processes through colicin intoxicationMathematical Virology: A new mathematical approach to viral evolution grounded in experimentMolecular level regulation of BIP, a central molecular chaperone in the ERProbing biomolecular interactions by combining ETD-tandem mass spectrometry with chemical footprinting methodologiesReaction intermediates in the O2 activation mechanism of an extradiol dioxygenase: visualising catalytic protons and active site dynamics in crystalloSingle-molecule assays of the assembly/disassembly mechanisms of ssRNA viruses - Tools for screening novel anti-viralsStructure and dynamics of oligomeric intermediates in amyloid assemblySuper resolution imaging of protein dynamics and functions in physiology and diseaseTesting novel anti-viral strategies in plantsThe development and application of complementary biophysical methods enabling the study of biomacromolecular dynamicsThe initiation of mRNA degradation by the direct entry of RNase E and the degradosome with implications for non-nucleolytic gene controlThe roles of the pre-genomic RNA in Hepatitis B Virus nucleocapsid assembly.
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Astbury Centre for Structural Molecular Biology
research centre at the University of Leeds
location
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research centre at the University of Leeds
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research centre at the University of Leeds
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research centre at the University of Leeds
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قسم أكاديمي
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Astbury Centre for Structural Molecular Biology
@en
Astbury Centre for Structural Molecular Biology
@en-ca
Astbury Centre for Structural Molecular Biology
@en-gb